From a drug store established in 1950 in Hue, OPV became the largest pharmaceutical company in Vietnam in the 1970s and was the sole licensee for both sales and production for those companies. leading multinational pharmaceutical companies such as Bayer, Ciba Geigy, Mead Johnson, Merck Sharp & Dohme, Roche, Sandoz, Smith Kline & French, Upjohn, and Warner Lambert.
During that time, OPV built the most modern and large scale pharmaceutical factory; and became a partner with Nestle Group to build a milk factory for children in Vietnam.